California providers: Quest Diagnostics is proud to offer the GDSP cfDNA Panel as part of the California Prenatal Screening Program. Learn More →

QNatal® Advanced
noninvasive prenatal screening

Empowering better access to important prenatal screening

QNatal® Advanced is a noninvasive cell-free DNA (cfDNA) prenatal screen that screens for the most common fetal aneuploidies, including Down syndrome. In addition, if elected, QNatal Advanced can screen for certain microdeletions and/or fetal sex. Test code 92777

While many may offer prenatal screening, we deliver on the promise of making advanced screening more accessible.

qnatal advanced heroqnatal advanced hero

Prenatal screening should be available to all. 76% of patients pay less than $99.a

Access made easy

We make QNatal Advanced testing more accessible with cost transparency, financial tools, and support at every step. It starts by being in-network with the majority of health plans nationwide.

Understanding costs

This QNatal Advanced Cost Estimator provides estimated out-of-pocket costs specific to each woman and her pregnancy, her health plan, and her deductible, resulting in a personalized estimate.

Prior authorization (PA) services for all orders

Orders are routed automatically to our Specialty Testing Services (STS) team who works with a patient’s health plan to determine coverage and need for prior authorization. Email Preauthorization_PrenatalScreening@QuestDiagnostics.com or call 1.888.445.5011.

Flexible financial options

We are committed to helping your patients receive prenatal screening at a lower cost.

For the insured—with coverage and appropriate ICD-10 diagnosis codes, patients can pay as little as $0 based on their insurance plan
For the insured who experience a denial—if the health plan denies QNatal Advanced as a “noncovered service,” the patient should pay no more than $300
For the uninsured—uninsured patient price (UPP)b available in all states for qualified patients
For the insured—with coverage and appropriate ICD-10 diagnosis codes, patients can pay as little as $0 based on their insurance plan
For the insured who experience a denial—if the health plan denies QNatal Advanced as a “noncovered service,” the patient should pay no more than $300
For the uninsured—uninsured patient price (UPP)b available in all states for qualified patients
76% of patients pay less than $991
76% of patients pay less than $991

Helping provide patients better peace of mindc

QNatal® Advanced is a noninvasive cell-free DNA (cfDNA) prenatal screen that screens for the most common fetal aneuploidies, including Down syndrome. In addition, if elected, QNatal Advanced can screen for certain microdeletions and/or fetal sex. Test code 92777

High-quality prenatal screening

A simple maternal blood draw performed as early as 10 weeks into the pregnancy
Strong performance characteristicsc and low no-call ratesd
Part of our comprehensive portfolio of more than 3,500 tests, including 900+ advanced genetic screens, to help you and your patients make informed decisions at every stage of their lives

Comprehensive screening, easy-to-read results

Clearly reported results as positive or negative for the trisomies in a concise, easy-to-read report
Clinical consultation available from certified genetic counselors for results interpretation—call 1.866.GENE.INFO (1.866.436.3463)

Helping provide patients better peace of mindc

QNatal® Advanced is a noninvasive cell-free DNA (cfDNA) prenatal screen that screens for the most common fetal aneuploidies, including Down syndrome. In addition, if elected, QNatal Advanced can screen for certain microdeletions and/or fetal sex. Test code 92777

High-quality prenatal screening

A simple maternal blood draw performed as early as 10 weeks into the pregnancy
Strong performance characteristicsc and low no-call ratesd
Part of our comprehensive portfolio of more than 3,500 tests, including 900+ advanced genetic screens, to help you and your patients make informed decisions at every stage of their lives

Comprehensive screening, easy-to-read results

Clearly reported results as positive or negative for the trisomies in a concise, easy-to-read report
Clinical consultation available from certified genetic counselors for results interpretation—call 1.866.GENE.INFO (1.866.436.3463)

Access to advanced screening and accurate results from a single source.c

That’s our promise to you and your patients.

Download our brochure

Access to advanced testing and reliable results from a single source.

That’s our promise to you and your patients.

Download our brochure

Click here for more information and to order QNatal Advanced

a Claims analysis. Data on file. Quest Diagnostics, 2020.

b Alternative UPP pricing is available in Florida, New Hampshire, Massachusetts, Maine, Rhode Island, Vermont, and Texas

c QNatal® Advanced is a cell-free DNA test that screens for increased risk of certain fetal chromosomal abnormalities that may cause birth defects, including Trisomy 21 (Down Syndrome), Trisomy 18, Trisomy 13, and certain sex chromosome abnormalities (ie, 45,X, 47,XXY, 47,XXX, and 47,XYY). In addition, if selected as an option, QNatal Advanced can screen for certain microdeletions (ie, 22q, 5p, 1p36, 15q, 11q, 8q, and 4p) that may cause birth defects, and/or for fetal sex. This test does not assess the risk of fetal anomalies such as neural tube defects or ventral wall defects. QNatal Advanced must not be used earlier than 10 weeks into pregnancy.

QNatal is a “screening” test, not a diagnostic test, and therefore all positive/increased risk results should be followed by genetic counseling and further diagnostic testing and procedures, when clinically indicated. Pregnancy management decisions should not be based on the results of a cfDNA test alone. As with any test, there may be false positives or false negatives. The positive predictive value of the screening test varies by genetic marker, and may be lower for rare conditions. Performance data for the QNatal Advanced may be obtained by contacting Quest Diagnostics at 1.866.GENE.INFO (1.866.436.3463).

QNatal Advanced is a laboratory developed test that has been developed and validated, pursuant to the Clinical Laboratory Improvements Amendments of 1988 (CLIA), and as such it has not been reviewed by FDA.

d Guy C, Haji-Sheikhi F, Rowland CM, et al. Prenatal cell-free DNA screening for fetal aneuploidy in pregnant women at average or high risk: Results from a large US clinical laboratory. Mol Genet Genomic Med. 2019;7(3):e545. doi:10.1002/mgg3.545 (finding a no-call rate of 3.5%; several authors affiliated with Quest Diagnostics). “No call rate” refers to the percentage of samples for which results could not be reported.

This test is offered as QNatal Advanced in all states other than California.

Test codes may vary by location. Please contact your local laboratory for more information.

Image content features models and is intended for illustrative purposes only.